Deion Sanders, known to fans as “Coach Prime,” has always been a larger-than-life figure. From his electrifying days as an NFL Hall of Famer to his transformative role as head coach of the Colorado Buffaloes, Sanders has never shied away from the spotlight. But behind the bravado and charisma lies a man who has faced significant health challenges, particularly in recent years. His ongoing battle with medical issues, including blood clots and surgeries, has raised concern among fans, but Sanders’ relentless spirit continues to shine through. Here’s a look at his health journey, his recent updates, and what it means for his future.
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A History of Health Struggles
Deion Sanders’ health challenges are not new. Back in 2021, while coaching at Jackson State, he faced a serious ordeal with blood clots in his left leg, which led to the amputation of two toes. The issue stemmed from a hereditary condition, as Sanders has noted that his mother and uncles also dealt with blood clots. In 2023, he underwent emergency surgery to address persistent blood clots in both legs, a procedure that sidelined him from key events like the Pac-12 media days. These health issues have been physically taxing, with Sanders undergoing a total of 12 surgeries to manage pain and improve circulation. Despite these setbacks, Sanders has remained open about his journey, sharing updates through social media and his son’s YouTube channel, Well Off Media.
Recent Health Concerns Spark Worry
In June 2025, reports surfaced that Sanders was dealing with an unspecified health issue that kept him away from the Colorado campus. He missed the team’s annual summer football camps and canceled a speaking engagement at the Sickle Cell Disease Research and Educational Symposium. His son, Deion Sanders Jr., shared during a YouTube livestream that his father was “feeling well” but didn’t disclose specifics, promising more details soon. Sanders’ absence from public appearances since April fueled speculation, especially given his history of serious health complications. Fans took to social media to express concern, with many sending prayers and well wishes. On June 11, Sanders addressed these concerns on X, reassuring fans, “Wow, I am truly blessed for the abundance of well wishes… I can assure you all that everything is OKAY and will continue to be so.”
A Positive Turn and Return to Boulder
By July 2025, Sanders signaled a positive shift. In a social media post on July 25, he declared, “Back and Feeling Great!” alongside a video shared by Deion Jr. showing him walking, shooting hoops, and even taking a tennis lesson. While he admitted he wasn’t “all the way recovered,” his return to the Colorado campus for fall camp marked a significant milestone. A press conference scheduled for July 28, 2025, with his medical team from CU Anschutz and UCHealth, promised to provide more clarity on his condition and team updates. Sanders’ optimism and energy in recent videos suggest he’s on the mend, ready to lead the Buffaloes into the 2025 season, which kicks off against Georgia Tech on August 29.
The Role of Family and Faith
Throughout his health challenges, Sanders has leaned heavily on his family and faith. His son, Deion Jr., has been by his side in Texas, documenting his recovery and offering glimpses into his progress. Sanders’ children, including Shedeur and Shilo, have also been vocal supporters, though they’ve respected his privacy by not sharing specifics. In his own words, Sanders credits his faith for carrying him through, often saying, “God got me like no other.” His mother, Connie Knight, instilled a work ethic that drives him to keep pushing forward, even when advised to rest. In a February 2025 Instagram post, Sanders reflected on her influence, saying he couldn’t recall her taking a day off, which fuels his determination to keep going.
Looking Ahead with Resilience
As Sanders prepares for his third season with the Colorado Buffaloes, his health remains a focal point, but so does his resilience. Despite losing key players like Shedeur Sanders and Travis Hunter to the NFL Draft, he’s focused on guiding a new roster, with quarterbacks Kaidon Salter and Julian Lewis vying for the starting role. His health journey has been a testament to his ability to overcome adversity, from toe amputations to multiple surgeries. Sanders’ openness about his struggles, combined with his refusal to let them define him, continues to inspire fans and players alike. As he said, “I’m not shy about what transpired. I’m back. I’m fighting back, baby.” With a press conference set to shed more light, the hope is that Coach Prime is on the path to full recovery, ready to lead with the same fire that’s defined his career.